A Letter to my Docs

Today I landed on some new ideas that we pray may be of use for my recovery from this serious illness.  I’ll let you read it for yourself.  Lord willing, I will get well soon!  Take care Gentle Readers and Godspeed.  I am praying for you too this day.  With love, JJ

Seizure attacks kept me up all night last night and my sleep cycle is now upside down again.  I had to stop the Buck Shot (i.e. nutritional injection) due to numbness in my right hip that has yet to resolve; ruling out this week if there is any possibility that it is the Thyroidea.  I have not slept since yesterday.
The “Holy Cow” moment came as follows.  Lying in bed unable to sleep I realized that my dog eats Canadian goose poop on occasion.  I researched parasites/infections from goose poop and only toxoplasmosis seemed to be an infection that I could have gotten from her.  Sometimes my stool smells like hers!
 
Looking into this further I found the following article about latent toxoplasmosis in humans:
 
 
Of interest were the remarks about hepatitis in acute toxoplasmosis infection (yes, October 11, 2011 this illness began with viral hepatitis after contaminated reservoir water exposure) and the effect the parasite can have on a variety of brain cells including astrocytes and neurons.  In a study involving 17 countries, cryptogenic (no known cause) epilepsy is 4.8 times more prevalent among toxoplasma seropositive persons.  “There are evidences that t. gondii infection has the greatest impacts on the hippocampus and amygdala.  And get this:
“Another likely hypothesis which t. gondii could cause neurodegenerative and psychiatric disorders, is modulation of different neurotranmitters especially dopamine in brain by the parasite (reference).  The t. gondii genome is known to contain 22 aromatic amino acid hydroxylases that potentially could directly affect dopamine and/or serotoinin biosynthesis.”
Are not phenylalanine, tryptophan, and tyrosine AAAs?  (My naturopath has prescribed phenylalanine to help with dopamine trafficking!)
“Treatment with a dopamine reuptake inhibitor (GBR 12909) alters the behavior of the mice infected with t. gondii (reference).”  [Sounds like my HC7 treatment plan . . .]
“Furthermore, t. gondii has two genes encoding tyrosine hydroxylase which that produces L-DOPA (reference).”
“Likewise, inflammatory responses are the innate defense against t. gondii infection (reference)  [Got plenty of inflammation; this statement refers to psych disorders.]
AND NOW FOR A REFERENCE TO AUTOIMMUNE DISORDERS:  “There is evidence that t. gondii infected astrocytes and microglial cells release of IL-1a, IL-6, and granulocyte/macrophage colony stimulating factor (GM-CSF).  On the other hand, IL-6 may mediate the exacerbation of autoimmune disorders in the CNS; in addition, there is strong association between IL-6 and neurotransmitter production (ref).  Furthermore, in vitro stimulation of neurons to secrete dopamine and probably other catecholamines by IL-6 were also reported (ref).”  [Multiple brands of GABA made me worse.  I was recently diagnosed with an autoimmune disorder.]
RELATED TO MY STATEMENT ON FACEBOOK (to my naturopath) THAT 5-HTP MADE SEIZURES WORSE:  “On the other hand tryptophan is an essential amino acid for t. gondii replication (ref).”
Kynurenic Acid (KYNA) was 12.5 on my last Nutreval (normal is below 7.1)  “Astrocytes play a pivotal role in the production of KYNA in the CNS, because astrocytes are the main source of KYNA (ref).  Likewise, astrocytes are one of the most important cells that invade by t. gondii . . .”  [Holy cow.]
JUST WHEN IT COULD NOT GET ANY CLEARER, READ THIS FROM ANOTHER SOURCE AS NOTED BELOW:
“The genome of the protozoan parasite Toxoplasma gondii was found to contain two genes encoding tyrosine hydroxylase; that produces l-DOPA. The encoded enzymes metabolize phenylalanine as well as tyrosine with substrate preference for tyrosine. Thus the enzymes catabolize phenylalanine to tyrosine and tyrosine to l-DOPA.”
 
Alrighty then, time to get me tested for toxoplasmosis right away!  My dog eats goose crap.  Not sure if it’s worth it to get her tested or not so I’ll ask the vet today.
Please advise how to proceed.  Every night and morning, my life is hell.  (Signed JJ)
UPDATE:  Our dog was negative in an office screening of her poop for parasites.  Still in hot pursuit to rule out this infection due to exposures mentioned above.  Stay tuned peeps!  JJ
12 step, promises, experience, benefit others, AAACOA, ACOA, Al Anon, Adult Child,

A Pause in the Middle of the Storm

Best ceremony photo

I am grateful to report that I received my Advanced Master Gardener designation from the Cooperative Extension Office of Purdue University, Fort Wayne yesterday. God is good.

To become a Master Gardener in a University-affiliated program in the United States, a person takes a three-month course, six hours per week, successfully completes all class assignments and projects, takes a comprehensive exam, and completes 48 hours of related volunteer work.  Each additional rank of recognition, requires additonal volunteer hours and educational classes.  For me, the volunteer work and training was accomplished while undergoing treatment and complications of Lyme Disease!  How does that work?  By the grace of our Lord, Jesus Christ alone!

Sometimes I would stop at the Extension Office to water the Vegetable Garden in the cold or extreme heat because it needed me to do so as one of the members of the Vegetable Garden team.  Sometimes I went to an educational class a “shred-over-nauseous” in the evening just to get out of the house and be around people.  And the Lord allowed me to sit at my computer last Winter and research a beautification project for my housing association . . . to help me get out of bed!  I remain grateful for this opportunity to accomplish something meaningful to me and even more grateful for the love and support of my husband, Steve.

Steve encouraged me to cut back on my work schedule and take the Master Gardener class before illness first struck in October of 2011.  After that it was the friendship of our special project group within the class that kept me going as viral hepatitis set in:  Jim Battin, James Poiry, Sue Hauck, Cindy Trygg, and Beth Fiato.  Sue Hauck is in the picture above, to my left (I’m the gal in black) and Cindy Trygg is in the audience:  two sweet gardeners extraordinaire that took an interest in me and kept the friendly connections going after the class ended.  When I began treatment for Lyme Disease in January of 2012, Fran and Karen Yorio and Bill Diedrich joined what was to become the Willow Run Community Association Beautification Project and kept it all going with great support and feedback when the going got tough for me.  Later in the year, Cindy, Jim Neuhouser and Jo Ellen Smith allowed me to work at my own pace and sometimes alone late in the day to hang in there this past summer with the Veggie Garden team.   These crazy hours of volunteering and ongoing training, with the support of kindred spirited Master Gardeners and Interns, helped me earn this designation.  Thank you!  You da best!  I could not, would not have been able to do anything without your friendship.

Last night was a pause, a moment to reflect, despite the ongoing chaos that is in our home right now.  We ate banquet food and listened to a presentation on prairie management from Blue Heron Ministries, Inc.  Just that we were out for a special night then returned to the hotel room to crash while our home begins the mold restoration process.  Throughout this past 1 1/2 year, I am grateful to know that gardening, one of my favorite passions (with Steve being number one, of course!) will be there when the dust settles (and goes away!) in our home.  Maybe this Spring I’ll plant a commemorative specimen to represent this amazing journey of discovery, of healing.

Hmmmmm . . . Any ideas what that should be?  :J